Measure out all your ingredients: ketchup, BBQ sauce, hot sauce, apple cider vinegar, brown sugar, garlic powder, onion powder, smoked paprika, and black pepper will help the process go smoothly.
Add all your ingredients to a small saucepan over low to medium-low heat. Start with one tablespoon of water. Wait to add the second tablespoon until you see how the sauce looks after heating. Whisk everything until it is smooth.
Bring the sauce to a low simmer, not a rolling boil. Simmer gently for about five to eight minutes. Stir occasionally to prevent sticking. The sauce will change color slightly as it heats.
This step is crucial. After the sauce simmers, taste it. If it is too sweet, add more hot sauce or a tiny splash of vinegar. If it is too tangy, add a little more brown sugar. If it needs more smoke, add a pinch more smoked paprika. If it is too thick, stir in the second tablespoon of water.
Pour the sauce into a glass jar and let it cool down to room temperature. Then cover the jar and refrigerate it for at least 2 hours.
Letting it sit overnight is even better, as it helps the flavors blend. Before serving, heat the sauce in a small saucepan or in the microwave. Pour it generously over fried chicken, wings, or whatever else you like.